TOPICAL PROTEASE INHIBITOR INCREASES TUMOR-FREE AND OVERALL SURVIVAL IN CD4-DEPLETED MOUSE MODEL OF ANAL CANCER

Topical Protease Inhibitor Increases Tumor-Free and Overall Survival in CD4-Depleted Mouse Model of Anal Cancer

Patients with immunodeficiencies and older age are at an increased risk of anal cancer.Transgenic K14E6/E7 mice with established high-grade anal dysplasia were treated topically at the anus with the protease inhibitor saquinavir (SQV) in the setting of CD4+ T-cell depletion to mimic immunodeficiency.To ensure tumor development, specific groups were

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INTELLECTUAL PROPERTY IN INTERNATIONAL PRIVATE LAW

One of the biggest problems in the matter of intellectual propertv and private international law occurs in a dilemma, if the citizen from other country can gain the protection of their rights in the field of intellectual propertv in Serbia, and under what conditions, and is this also applies to our national abroad, as well as registration and prote

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Stackelberg Equilibrium Premium Strategies for Push-Pull Competition in a Non-Life Insurance Market with Product Differentiation

Two insurance companies I 1 , I 2 with reserves R 1 ( t ) , R 2 ( t ) compete for customers, such that in a suitable differential valhalla axys game the smaller company I 2 with R 2 ( 0 ) < R 1 ( 0 ) aims at minimizing R 1 ( t ) − R 2 ( t ) by using the premium p 2 as control and the larger I 1 at maximizing eeboo coupons by using p 1.Dedu

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